Lines of Research
Research activities are on the following topics:
Dermal and transdermal drug delivery
- Development and characterization of innovative formulations for drug delivery to the skin tissue
- Study of strategies to promote absorption through the stratum corneum
- Formulation and development of transdermal patches
- Formulation, characterization and evaluation of dermal accumulation of cosmetic actives
Ocular and buccal drug delivery
- Ex-live for the study of ocular drug delivery
- Mucoadhesion
- Formulation and characterization of nanocarriers for ocular and buccal drug delivery
- Development and characterization of polymeric films for controlled release of biomolecules
Reducing the environmental impact of drugs
- New sequential release systems capable of reducing the excretion of drugs in active form
- Methods to increase oral absorption of poorly soluble molecules
Nasal and pulmonary drug administration
- Formulation of drugs and biomolecules for pulmonary administration in solid form, liquid or pressurized
- Design and development of pressurized dose-measured devices (pMDI) formulated with new environmentally friendly propellants for pulmonary inhaled drug delivery
- Study on the advantages and methods of administration of probiotics to the respiratory system
- Development of new techniques and models for studying the deposition/dissolution/absorption of formulations directed to the respiratory system
- Development of formulations for nasolabial administration to the nose-brain
Nanomedicine
- Development and characterization of lipid-based nanoparticle systems, polymeric or hybrid equipped with high biocompatibility for alternative administration to the parenteral route
- Development of lipid-based, inorganic and hybrid nucleic acid delivery systems for therapeutic or vaccine use for non-parenteral administration
